AI Unlocks New Front in Pain Medication Discovery

​​🤖 AI Revolutionizing the Discovery of New Pain Medications #BBSafery 💡 A team of researchers, led by Yuxin Yang, has introduced an advanced AI framework named LISA-CPI to discover new pain treatments. This groundbreaking model combines molecular imaging and protein structures to find drug candidates targeting specific G-protein-coupled receptors (GPCRs) responsible for pain signaling, offering hope for non-opioid painkillers. 🌍 Chronic pain is a global issue, and current treatments like opioids carry risks of addiction. The LISA-CPI model was trained on over 10 million molecules and tested on thousands of ligands, showing a 20% improvement in accuracy compared to existing models. This AI-driven method could significantly speed up drug discovery, focusing on non-opioid medications to minimize side effects. 💊 One of the exciting breakthroughs of LISA-CPI is its ability to identify repurposable drugs, like methylergometrine, and gut metabolites such as citicoline, which show potential in pain relief. These findings pave the way for new therapies that target pain without the dangerous side effects of opioids. 🔬 LISA-CPI also sheds light on the role of gut microbiota in pain management, suggesting that gut health could play a role in controlling pain. This innovative approach could lead to safer, more effective treatments in the future. 👉 Link: https://bbgate.com/threads/how-ai-is-uncovering-new-pain-medications.12915/ 🧅 Link: http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/how-ai-is-uncovering-new-pain-medications.12915/ Breaking Bad Forum │ TG Channel